Take a breath. Here’s what to do.

I had unprotected sex.
Now what?

You’re not the first person to be here. Most bacterial STIs are curable, and many viral ones are manageable with treatment. Here’s the plan.

General health information based on CDC and USPSTF guidelines. Not medical advice or a diagnosis. If you have symptoms or a known exposure, see a licensed clinician.

1
Right now: Consider doxy-PEPWithin 72 hours

Doxycycline post-exposure prophylaxis (200 mg taken within 72 hours) reduced bacterial STI incidence by roughly 65% in trial populations of MSM and trans women on PrEP (CDC, June 2024). Evidence in cisgender women is more limited. A telehealth clinician can decide whether it’s appropriate for you and prescribe it.

Typical total ~$35 (telehealth consult + generic doxycycline). Final cost varies by provider and pharmacy.

2
This week: Get testedChlamydia & gonorrhea reliable now

Different tests have different detection windows. Typical timelines below; talk to a clinician about what’s right for your situation.

Chlamydia & GonorrheaNAAT may detect within ~5–7 days; longer for some sites
ACA $0*
HIV (4th gen Ag/Ab)Baseline now; conclusive results typically by ~45 days
ACA $0*
SyphilisTypically detectable by 3–6 weeks
ACA $0*
Hepatitis B & CTypically detectable by 3–6 weeks
ACA $0*

*ACA-compliant plans typically cover screening for these STIs at no cost-sharing when ordered as preventive care; coverage and eligibility depend on your plan.

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3
4-6 weeks: Retest for HIVPut a calendar event on your phone

4th-generation HIV antigen/antibody tests are typically considered conclusive by ~45 days post-exposure. Set a calendar reminder for the right window. (Optional reminder emails are coming later.)

4
3 months: Full retestCDC recommends

CDC recommends rescreening at 3 months after a positive chlamydia or gonorrhea result because reinfection is common (published estimates range roughly 10–20%). A repeat panel can confirm a result.

Most bacterial STIs are curable with antibiotics, and many viral ones are manageable with treatment. The hardest part is what you’re doing right now — deciding to deal with it.

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Based on CDC STD Screening Guidelines. Not medical advice. Always consult a healthcare provider.